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Image Search Results
Journal: Archives of Pathology & Laboratory Medicine
Article Title: The Biospecimen Preanalytical Variables Program: A Multiassay Comparison of Effects of Delay to Fixation and Fixation Duration on Nucleic Acid Quality
doi: 10.5858/arpa.2018-0172-oa
Figure Lengend Snippet: Figure 6. DNA quality assessment of tumor biospecimens from delay to fixation (DTF) (A through C) and time in fixative (TIF) (D and E) experimental modules by the KAPA assay. Box plots represent mean Q-ratios (129/41-bp amplicons) of DNA isolated from case-matched snap-frozen and formalin-fixed and paraffin-embedded (FFPE) kidney (A and D), ovarian (B and E), and colon (C) tumor biospecimens processed under DTF (1, 2, 3, 12 hours) and TIF (6, 12, 23, 72 hours) experimental modules. Mean Q-ratios were statistically different within FFPE DTF and TIF modules (P , .001), with the exception of ovarian TIF biospecimens.
Article Snippet: The
Techniques: Isolation